Cayaponia
   quinqueloba (Raf.) Shinners (five lobe cucumber)

 Citrullus
   colocynthis (L.) Schrad. (colocynth)
   lanatus var. citroides (Bailey) Mansf.
   lanatus var. lanatus

 Coccinia
   grandis (L.) Voigt (ivy gourd)

 Cucumis
   anguria var. longaculeatus J.H. Kirkbride (bur cherkin, west indian cherkin)
   dipsaceus C.G. Ehrenb. ex Spach (hedgehog-gourd)
   melo L. (muskmelon)

 Cucurbita
   digitata Gray (finger leaf gourd)
   foetidissima Kunth (buffalo gourd, stinking gourd, calabacilla loca, missouri gourd, foetid wild pumpkin)
   pepo var. ovifera (L.) Alef. (ornamental gourd)
   pepo var. texana (Scheele) D. Decker (texas gourd)

 Cyclanthera
   dissecta (Torr. & Gray) Arn. (cutleaf cyclanthera, bur cucumber)

 Echinocystis
   lobata (Michx.) Torr. & Gray (wild mockcucumber, wild cucumber)

 Echinopepon
   wrightii (Gray) S. Wats. (wright's mockcucumber, wild balsamapple)

 Ibervillea
   lindheimeri (Gray) Greene (lindheimer globeberry, balsam gourd, balsamapple)
   tenuisecta (Gray) Small (slimlobe globeberry, deerapples)

 Lagenaria
   siceraria (Molina) Standl. (white-flowered bottlegourd, calabash gourd)

 Luffa
   aegyptiaca P. Mill. (sponge gourd)

 Melothria
   pendula var. pendula (drooping mellonette, creeping cucumber, green melonette, melonette)

 Momordica
   balsamina L. (balsamapple)
   charantia L. (wild balsamapple, balsam-pear)

 Sicyos
   ampelophyllus Woot. & Standl. (streamside burr cucumber)
   angulatus L. (one-seeded bur-cucumber, wall bur-cucumber)
   glaber Woot. (smooth bur-cucumber)
   laciniatus L. (cut leaf burr cucumber)
   microphyllus Kunth (little leaf burr cucumber)
   parviflorus Willd. (small-flower bur-cucumber)